全文获取类型
收费全文 | 4365篇 |
免费 | 381篇 |
国内免费 | 169篇 |
出版年
2024年 | 9篇 |
2023年 | 103篇 |
2022年 | 86篇 |
2021年 | 146篇 |
2020年 | 172篇 |
2019年 | 225篇 |
2018年 | 197篇 |
2017年 | 151篇 |
2016年 | 171篇 |
2015年 | 155篇 |
2014年 | 202篇 |
2013年 | 325篇 |
2012年 | 170篇 |
2011年 | 172篇 |
2010年 | 172篇 |
2009年 | 246篇 |
2008年 | 217篇 |
2007年 | 225篇 |
2006年 | 219篇 |
2005年 | 178篇 |
2004年 | 138篇 |
2003年 | 134篇 |
2002年 | 114篇 |
2001年 | 107篇 |
2000年 | 80篇 |
1999年 | 80篇 |
1998年 | 87篇 |
1997年 | 53篇 |
1996年 | 55篇 |
1995年 | 56篇 |
1994年 | 60篇 |
1993年 | 65篇 |
1992年 | 52篇 |
1991年 | 52篇 |
1990年 | 29篇 |
1989年 | 30篇 |
1988年 | 26篇 |
1987年 | 18篇 |
1986年 | 15篇 |
1985年 | 22篇 |
1984年 | 22篇 |
1983年 | 13篇 |
1982年 | 15篇 |
1981年 | 13篇 |
1980年 | 12篇 |
1979年 | 7篇 |
1978年 | 7篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1975年 | 3篇 |
排序方式: 共有4915条查询结果,搜索用时 31 毫秒
101.
102.
Debarati Chattopadhyay Joel James Debasish Roy Soumadeep Sen Rishita Chatterjee Kavitha Thirumurugan 《Fly》2015,9(1):16-21
Drosophila melanogaster is an ideal model organism for developmental studies. This study tests the potential of semolina-jaggery (SJ) diet as a new formulation for bulk rearing of flies. Semolina and jaggery are organic products obtained from wheat endosperm and cane sugar, respectively. Semolina is a rich source of carbohydrates and protein. Jaggery has a high content of dietary sugars. Moreover, preparation of semolina jaggery diet is cost-effective and easy. Thus, the current study aimed to compare survival and developmental parameters of flies fed the SJ diet to flies fed the standard cornmeal-sugar-yeast (CSY) diet. SJ diet enhanced survival of flies without affecting fecundity; male flies showed increased resistance to starvation. A higher number of flies emerged at F2 and F3 generation when fed the SJ diet than when fed the control CSY diet. SJ diet did not increase fly body weight and lipid percentage. Therefore, SJ diet can be used for bulk rearing of healthy flies at par with the standard cornmeal-sugar-yeast diet. 相似文献
103.
Evolution of anuran brains: disentangling ecological and phylogenetic sources of variation 下载免费PDF全文
Variation in ecological selection pressures has been implicated to explain variation in brain size and architecture in fishes, birds and mammals, but little is known in this respect about amphibians. Likewise, the relative importance of constraint vs. mosaic hypotheses of brain evolution in explaining variation in brain size and architecture remains contentious. Using phylogenetic comparative methods, we studied interspecific variation in brain size and size of different brain parts among 43 Chinese anuran frogs and explored how much of this variation was explainable by variation in ecological factors (viz. habitat type, diet and predation risk). We also evaluated which of the two above‐mentioned hypotheses best explains the observed patterns. Although variation in brain size explained on average 80.5% of the variation in size of different brain parts (supporting the constraint hypothesis), none of the three ecological factors were found to explain variation in overall brain size. However, habitat and diet type explained a significant amount of variation in telencephalon size, as well in three composite measures of brain architecture. Likewise, predation risk explained a significant amount of variation in bulbus olfactorius and optic tecta size. Our results show that evolution of anuran brain accommodates features compatible with both constraint (viz. strong allometry among brain parts) and mosaic (viz. independent size changes in response to ecological factors in certain brain parts) models of brain size evolution. 相似文献
104.
《Cytokine》2015,74(2):265-269
IntroductionObesity is associated with low-grade systemic inflammation which is thought to trigger the development of comorbidities such as type 2 diabetes. The soluble receptor for advanced glycation end products (sRAGE) belongs to the innate immune system and has been linked to obesity, recently. The aim of the present study was to examine whether serum sRAGE concentrations are related to the grade of weight loss and improvement of insulin resistance due to a very low calorie diet (VLCD).Methods22 severe obese subjects (Median Body Mass Index (BMI): 44.5 kg/m2) were included in a dietary intervention study of 6 month, consisting of a very low calorie formula diet phase (VLCD: 800 kcal/d) for 12 weeks and a following 12 week weight maintenance phase. Fasting glucose, fasting insulin, adiponectin, leptin and sRAGE were determined from sera. Insulin sensitivity was estimated by Homeostasis Model Assessment (HOMA) index and leptin-to-adiponectin-ratio (LAR).ResultsMean body weight reduction by VLCD accounted to 21.7 kg with a significant improvement of insulin resistance. At baseline, sRAGE serum levels were significantly inversely related to BMI (rS = −0.642, p = 0.001) and HOMA (rS = −0.419, p = 0.041). Of interest, sRAGE serum levels at baseline were significantly lower in study subjects with greater reduction of BMI (p = 0.017). In addition, a significantly greater HOMA reduction was observed in subjects with lower sRAGE serum levels at baseline (p = 0.006). Finally, correlation analysis revealed, that changes of sRAGE serum levels were significantly correlated to changes of BMI (rS = −0.650, p = 0.022) during intervention.ConclusionAnti-inflammatory sRAGE might be a potential future biomarker to predict weight loss and improvement of insulin resistance by a VLCD whereby lower baseline sRAGE serum levels indicate a better outcome of the dietary intervention. 相似文献
105.
106.
It has been estimated that the energy captured in one hour of sunlight that reaches our planet is equivalent to annual energy production by human population globally. To efficiently capture the practically inexhaustible solar energy and convert it into high energy density solar fuels provides an attractive ‘green’ alternative to running our present day economies on rapidly depleting fossil fuels, especially in the context of ever growing global energy demand. Natural photosynthesis represents one of the most fundamental processes that sustain life on Earth. It provides nearly all the oxygen we breathe, the food we consume and fossil fuels that we so much depend on. Imitating the reactions that occur at the early stages of photosynthesis represents the main challenge in the quest for construction of an efficient, robust, self-renewing and cost-effective ‘artificial leaf’. In this review we summarize the main molecular features of the natural solar energy converters, photosystem I and photosystem II, that allow them to operate at high quantum efficiencies, and thus inspire the smart matrix design of the artificial solar-to-fuel devices. We also discuss the main challenges that face the field and overview selected recent technological advances that have tremendously accelerated the race for a fully operational artificial leaf that could serve as a viable alternative to fossil fuels for energy production. 相似文献
107.
108.
本研究在原来CASA模型的基础上,对模型参数最大光能利用率和水分胁迫系数的算法进行了改进,利用改进后的CASA模型模拟了2010年内蒙古锡林郭勒盟草原植被净初级生产力(NPP),并用地面实测样方数据对改进后的模型进行精度验证。结果表明:改进的CASA模型可应用于内蒙古草原小尺度植被NPP的估测,模拟NPP值与地面实测值之间的相关性达到显著水平(R2=0.829,P0.05);2010年内蒙古锡林郭勒盟草原植被生长季(4—10月)NPP为284.64 g C·m-2·a-1,不同地区年均NPP相差较大,东北部东乌珠穆沁旗草原NPP高达411.11 g C·m-2·a-1,而西北部的二连浩特市草原NPP仅为158.87 g C·m-2·a-1;整体上,锡林郭勒盟草原的NPP由东向西逐步递减,这与该区域水热条件限制基本一致;由于降水量的时滞效应,该年度内NPP出现两次峰值;2010年锡林郭勒境内草原NPP集中分布在250~350 g C·m-2·a-1,草甸草原的NPP最大,典型草原次之,荒漠草原最小。 相似文献
109.
Effect of plant oils on quality parameters of Bactrocera tryoni (Froggatt) reared on liquid larval diet 下载免费PDF全文
M. Khan 《Journal of Applied Entomology》2015,139(4):280-288
Liquid larval diets have been developed for several tephritid fruit flies including Queensland fruit fly, Bactrocera tryoni (Frogatt) (Q‐fly). In liquid diets, wheat germ oil (WGO) is usually added to improve performance in some quality parameters of reared flies, especially flight ability. However, for some flies, other plant oils may be more readily available, cheaper or produce flies of superior performance. In the present study, four alternative types of plant oils – rice bran, canola, vegetable, and sesame – were incorporated into a fruit fly liquid larval diet to replace the currently used wheat germ oil and their efficacy on the quality parameters of reared Q‐fly was compared to diets containing wheat germ oil or no oil. The quality parameters included: total pupal yield (N), pupal recovery (%), larval duration (days), pupal weight (mg), adult emergence (%), adult fliers (%), rate of fliers (%), sex ratio (%), F1 egg/female/day and egg hatching (%). There were significant differences among treatments in performance of Q‐fly. Vegetable oil appeared better in terms of total pupal yield, percentage of pupal recovery, percentage of adult emergence, percentage of fliers, mean egg/female/day and % F1 egg hatch compared with other oil treatments, especially from that of WGO treated diet. The result suggests that WGO can be substituted with rice bran and vegetable oil to improve the liquid larval diet for rearing of B. tryoni, with vegetable oil being the best replacement. 相似文献
110.
The evolution of novel host use is unlikely to be constrained by trade‐offs or a lack of genetic variation 下载免费PDF全文
Zachariah Gompert Joshua P. Jahner Cynthia F. Scholl Joseph S. Wilson Lauren K. Lucas Victor Soria‐Carrasco James A. Fordyce Chris C. Nice C. Alex Buerkle Matthew L. Forister 《Molecular ecology》2015,24(11):2777-2793
The genetic and ecological factors that shape the evolution of animal diets remain poorly understood. For herbivorous insects, the expectation has been that trade‐offs exist, such that adaptation to one host plant reduces performance on other potential hosts. We investigated the genetic architecture of alternative host use by rearing individual Lycaeides melissa butterflies from two wild populations in a crossed design on two hosts (one native and one introduced) and analysing the genetic basis of differences in performance using genomic approaches. Survival during the experiment was highest when butterfly larvae were reared on their natal host plant, consistent with local adaptation. However, cross‐host correlations in performance among families (within populations) were not different from zero. We found that L. melissa populations possess genetic variation for larval performance and variation in performance had a polygenic basis. We documented very few genetic variants with trade‐offs that would inherently constrain diet breadth by preventing the optimization of performance across hosts. Instead, most genetic variants that affected performance on one host had little to no effect on the other host. In total, these results suggest that genetic trade‐offs are not the primary cause of dietary specialization in L. melissa butterflies. 相似文献